Journal article
Exploring the association between BMI and mortality in Australian women and men with and without diabetes: the AusDiab study
SF Zahir, A Griffin, JL Veerman, DJ Magliano, JE Shaw, KAL Cao, AM Mehdi
Diabetologia | SPRINGER | Published : 2019
Abstract
Aims/hypothesis: There is conflicting evidence about the obesity paradox—the counterintuitive survival advantage of obesity among certain subpopulations of individuals with chronic conditions. It is believed that results supporting the obesity paradox are due to methodological flaws, such as collider bias. The aim of this study was to examine the association between obesity and mortality in Australian men and women. In addition, we explored whether obesity would appear to be protective if the analysis was restricted to a subpopulation with disease, and to discuss the potential role of collider bias in producing such a result. Methods: The examined cohort included 10,575 Australian adults (48..
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Awarded by Amgen
Funding Acknowledgements
SFZ is supported by an Endeavour Postgraduate Scholarship (4712). KALC is supported by a National Health and Medical Research Council (NHMRC) Career Development fellowship (GNT1087415). AMM is supported by a Postdoctoral Fellowship from JDRF (3-PDF-2016-198-A-N). JES is supported by a National Health and Medical Research Council (NHMRC) Senior Research Fellowship (APP1079438). DJM is supported by a National Health and Medical Research Council (NHMRC) Senior Fellowship (APP1118161). The funding sources were not involved in the design of the study, collection, analysis, and interpretation of data, writing the manuscript or the decision to submit it for publication.